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Contains 1 Component(s) Includes a Live Web Event on 11/23/2026 at 1:30 PM (EST)
Join Drs. Laura Carbone and Pritee Shrestha as they discuss MRONJ risk in individuals on pharmacotherapy for fracture prevention.
Learning Objectives coming soon.
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Contains 1 Component(s) Includes a Live Web Event on 10/27/2026 at 12:00 PM (EDT)
Join Dr. E. Michael Lewiecki as he presents, "Highlights of Osteoporosis Treatment from the Primer 10th Edition."
Join Dr. E. Michael Lewiecki as he presents, "Highlights of Osteoporosis Treatment from the Primer 10th Edition."
Learning Objectives:
1. Understand strategies for management of osteoporosis
2. Review challenges in the care of osteoporosis in older patients
3. Discuss current concepts for osteoporosis treatments in women-
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Contains 1 Component(s) Includes a Live Web Event on 09/29/2026 at 2:00 PM (EDT)
Join Dr. Sundeep Khosla as they discuss "The role of senescent cells in skeletal aging and repair " moderated by Dr. Matthew Prideaux
Join Dr. Sundeep Khosla as they discuss "The Role of Senescent Cells in Skeletal Aging and Repair " moderated by Dr. Matthew Prideaux
Learning Objectives:
1. Understand mechanisms driving cellular senescence in bone and other tissues
2. Define consequences of global and cell-specific senescent cell clearance on the skeleton
3. Define differences in mesenchymal versus immune cell senescent phenotypes
4. Describe progress and challenges to clinical translation of senolyticThis webinar is hosted by the ASBMR Muscle and Bone Disease Scientific Interest Group (SIG). The Scientific Interest Groups, brought to you by the Membership Engagement Committee (MEC), aim to empower members through fostering meaningful engagement and collaboration within specific research areas. SIGs are dedicated to promoting year-round connectivity, enhancing networking opportunities, and facilitating mentorship that advances careers. By ensuring inclusivity for all members, SIGs strive to provide exclusive benefits that extend beyond our Annual Meeting, creating a vibrant and supportive community for all.
$i++ ?>Dr. Sundeep Khosla
MD
Dr. Sundeep Khosla is the Dr. Francis Chucker and Nathan Landow Research Professor of Medicine and Physiology and a Mayo Foundation Distinguished Investigator. Dr. Khosla received his A.B. degree from Harvard College and his M.D. from Harvard Medical School. He was subsequently a resident in Internal Medicine and a fellow in Endocrinology at the Massachusetts General Hospital. In 1988 he moved to Mayo Clinic, where his research has focused on mechanisms of age-related bone loss and osteoporosis. Dr. Khosla has served as Director of the Center for Clinical and Translational Science and Dean for Clinical and Translational Science at Mayo Clinic. He has also served as Chair of the NIH SBDD Study Section, on the Councils of the National Institute on Aging and the National Institute of Arthritis and Musculoskeletal and Skin Diseases, and as President of the American Society for Bone and Mineral Research (ASBMR). Dr. Khosla has received numerous awards and honors for his work, including the Frederic C. Bartter Award for Clinical Investigation and the William F. Neuman Award for Outstanding Scientific Contributions from the ASBMR, the presentation of the Louis V. Avioli Plenary Lecture at the ASBMR annual meeting, the Outstanding Clinical Investigator Award and Plenary Lecture from the Endocrine Society, the Frontiers in Science Award from the American Association of Clinical Endocrinologists, the Jacobaeus Prize for outstanding research in Endocrinology, and election to the ASCI and AAP. Dr. Khosla has served as the Editor-in-Chief of Bone, as Associate Editor of the Journal of Bone and Mineral Research and as a member of the editorial boards for the Journal of Clinical Investigation, Journal of Bone and Mineral Research, Journal of Clinical Endocrinology and Metabolism, Bone, and Endocrine Reviews.
$i++ ?>Dr. Matthew Prideaux (Moderator)
Ph.D
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Contains 1 Component(s) Includes a Live Web Event on 09/21/2026 at 11:00 AM (EDT)
Join Drs. Claudine Blin-Wakkach and Julien Paccou as they present on osteoimmunology and gut microbiome.
Join Drs. Claudine Blin-Wakkach and Julien Paccou as they present on osteoimmunology and gut microbiome.
Learning Objectives:
1. Understand the cellular and molecular mechanisms by which intestinal inflammation and dysbiosis drive bone destruction, in particular in Crohn's disease and osteoporosis.
2. Understand the role of osteoclasts in sensing inflammatory signals, with a focus on their heterogeneity.
3. Evaluate the clinical consequences of gut inflammation on bone health, including osteoporosis, in patients with inflammatory bowel disease, particularly Crohn's disease.
4. Assess the therapeutic potential of probiotics to mitigate bone loss and improve skeletal outcomes.
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Contains 1 Component(s) Includes a Live Web Event on 09/14/2026 at 2:30 PM (EDT)
During this session, we share valuable tips on preparing for your trip to Boston, strategies to avoid meeting burnout, and how to maximize your networking opportunities.
During this session, we share valuable tips on preparing for your trip to Boston, strategies to avoid meeting burnout, and how to maximize your networking opportunities.
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Contains 1 Component(s)
Join Drs. Matthew Greenblatt and Dr. Federico La Manna in their 2-part webinar. Dr. Greenblatt will present on, "Getting Started with Performing Single Cell RNASeq Analyses on Musculoskeletal Cells" and Dr. La Manna will lead an interactive session where he will guide attendees step-by-step on how to do basic programming to generate a map of cell clusters and identify some top genes expressed by each cluster using a small data set.
Agenda
Dr. Matthew Greenblatt’s Presentation: 10 AM – 11 AM ET
Dr. Federico La Manna’s Workshop: 11 AM – 12:15 PM ETLearning Objectives:
- Understand the key experimental parameters impacting the analysis of single cell RNA sequencing data, and the strengths and weaknesses of this technique.
- Be able to analyze single cell RNA sequencing data using the Seurat platform.
- Consider key decision points in the analytic pipeline for single cell RNA sequencing data and how this impacts the results of the analysis.
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Contains 8 Component(s)
Long-Term Osteoporosis Treatment: Osteoclasts Biology
This topical learning module encompasses the formation, fusion, resorption, and signaling processes of osteoclasts to osteoblasts (coupling), along with the modulation of these processes by long-term antiresorptive therapy (e.g., RANKL inhibition). The available resources encompass Primer textbook chapters, ASBMR webinars/meeting sessions, podcasts, and recent JBMR/JBMR Plus articles on osteoclast mechanisms relevant to sustained therapy and treatment discontinuation.
Component List:
- Primer (10th Edition) Chapter
- Webinar: ASBMR Educational Series on Denosumab Therapy in Osteoporosis and Cancer - Episode 1
- Webinar: ASBMR Educational Series on Denosumab Therapy in Osteoporosis and Cancer - Episode #2
- JBMR Article: Osteoclast-derived coupling factors: origins and state-of-play Louis V Avioli lecture
- JBMR Article: Temporal patterns of osteoclast formation and activity following withdrawal of RANKL inhibition
- JBMR Article: The effects of denosumab on osteoclast precursors in postmenopausal women: a possible explanation for the overshoot phenomenon after discontinuation
- JBMR Article: Osteal macrophages support osteoclast-mediated resorption and contribute to bone pathology in a postmenopausal osteoporosis mouse model
- JBMR Plus Article: New Insights Into Osteoclast Biology
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Contains 14 Component(s) Recorded On: 10/28/2024
Long-Term Osteoporosis Treatment: Complications of Anti-Resorptive Therapy
The topical learning module addressing ‘Long-term osteoporosis treatment: Complications of anti-resorptive therapy’ in humans includes chapters from the Primer textbook, recorded webinars, and a clinical case workshop. Several original research articles are suggested, each an example of research on complications of anti-resorptive therapy.
Component List:
- Primer (10th edition) Chapter 79: BISPHOSPHONATES FOR POSTMENOPAUSAL OSTEOPOROSIS
- Primer (10th edition) Chapter 80: DENOSUMAB
- Primer (10th edition) Chapter 109: AFF (SURGICAL ASPECTS, PROPHYLACTIC NAILING OF THE CONTRALATERAL SIDE)
- Primer (10th edition) Chapter 135: MEDICATION RELATED OSTEONECROSIS OF THE JAW
- Webinar: Bisphosphonate treatment
- Webinar: Denosumab Therapy in Osteoporosis and Cancer
- Webinar: ASBMR ESI Clinical Case Workshop on Sequential Osteoporosis Treatment
- Annual Meeting recording: Clinical Symposium: Osteonecrosis of the Jaw
- JBMR Article: Bone Mineral and Organic Properties in Postmenopausal Women Treated With Denosumab for Up to 10 years
- JBMR Article: Risk of Osteonecrosis of the Jaw Under Denosumab Compared to Bisphosphonates in Patients With Osteoporosis
- JBMR Article: Managing Osteoporosis in Patients on Long‐Term Bisphosphonate Treatment: Report of a Task Force of the American Society for Bone and Mineral Research
- JBMR Article: A Population‐Based Registry Study of Extended Bisphosphonate Use: Minimal Shift After Landmark Publications About Shorter Treatment Duration
- JBMR Article: Atypical subtrochanteric and diaphyseal femoral fractures: second report of a task force of the American Society for bone and mineral research
- JBMR Article: Atypical fractures at non-classical sites associated with anti-resorptive therapy: a systematic review
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Contains 9 Component(s) Recorded On: 11/20/2023
Long-Term Osteoporosis Treatment: Transition off Denosumab
This topical module includes primer chapter, webinars, and original research from JBMR and JBMR Plus discussing skeletal complications following denosumab cessation and strategies to overcome these complications.
Component List:
- Primer (10th edition) Chapter 80: Denosumab
- Webinar: Episode #2 - Education Series on Denosumab Therapy in Osteoporosis and Cancer (Nov 20, 2023)
- Webinar: Episode #3 - Education Series on Denosumab Therapy in Osteoporosis and Cancer (Jan 11, 2024)
- Webinar: Final Episode - Education Series on Denosumab Therapy in Osteoporosis and Cancer (Jan 22, 2024)
- JBMR Article: Denosumab discontinuation in the clinic: implications of rebound bone turnover and emerging strategies to prevent bone loss and fractures.
- JBMR Article: Multiple Vertebral Fractures after Denosumab Discontinuation: Freedom and Freedom Extension Trials Addition Post-Hoc Analyses
- JBMR Article: Treatment with Zoledronate Subsequent to Denosumab in Osteoporosis: a randomized trial
- JBMR Article: Zoledronate for the prevention of bone loss in women discotinuing denosumab treatment
- JBMR Plus Article: Discontinuation of denosumab: Gradual decrease in doses preserves half of the bone mineral density gain at the lumbar spine
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Contains 1 Component(s)
Join Dr. Christopher Kovacs as he discusses, "Effects of Lactation and Pregnancy on Bone - Clinical and Basic".
Join Dr. Christopher Kovacs as he discusses "Effects of Lactation and Pregnancy on Bone - Clinical and Basic".
Learning Objectives:
1. Review how mineral and bone metabolism adapts during pregnancy and lactation to meet the fetal and neonatal demands for minerals, and the impact that these changes normally have on the healthy maternal skeleton.
2. Appreciate what systematic reviews have revealed about the epidemiology, risk factors, and recurrence rates for skeletal fragility that presents for the first time during pregnancy and especially lactation.
3. Determine a reasonable evidence-based approach to diagnosing and treating skeletal fragility during pregnancy and lactation.
4. Understand the uncertainties about when and if pharmacological therapy may be indicated for this rare condition and if so, which treatments might be used.
$i++ ?>Christopher S. Kovacs
MD
Memorial University Of Newfoundland
Dr. Christopher Kovacs is University Research Professor, and Professor of Medicine (Endocrinology and Metabolism), Obstetrics & Gynecology, and BioMedical Sciences, at Memorial University of Newfoundland in Canada. He trained at Queen’s University, University of Alberta, Harvard Medical School, Massachusetts General Hospital, and University of Melbourne. His clinical practice focuses on osteoporosis, hyperthyroidism, and thyroid cancer, while his research focuses on bone metabolism during pregnancy, lactation, and fetal development. Among numerous awards, he has received the Gold Medal in Medicine from the Royal College of Physicians and Surgeons of Canada and the Dr. Harvey Guyda Educator of the Year Award from the Canadian Society of Endocrinology and Metabolism. He has contributed over 150 research papers and 56 textbook chapters. He conceived and edited the multi-authored textbook, Maternal-Fetal and Neonatal Endocrinology: Physiology, Pathophysiology, and Clinical Management; a second edition appeared in 2025.
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